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KMID : 0358420110540080474
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Korean Journal of Obstetrics and Gynecology
2011 Volume.54 No. 8 p.474 ~ p.479
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Paget’s disease of the vulva treated by wide excision and reconstruction with skin grafts and flaps: Reports of three cases
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Cho Dong-Hyu
Lee Jeong-Heon
Roh Si-Gyun
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Abstract
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Extramammary Paget’s disease is a rare, slow-growing, non-invasive intraepithelial adenocarcinoma that occurs mainly in the elderly outside of the mammary gland. Paget’s disease of the vulva accounts for less than 1% of all vulvar malignancies. The standard treatment is wide local excision of the gross lesion. To prevent a relapse, wide excision with adequate margins is necessary not to leave pathologic lesions around margins of excision. However, since the excised area is too wide to cover all the exposed surface with a simple closure only, skin grafts and flaps can be very useful. We report successful treatment of three cases of extramammary Paget’s disease of the vulva using frozen section analyses of the margins during operation in order to attain Paget’s cells free margins and skin grafts and flaps to cover an extensive defects.
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KEYWORD
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Paget’s disease, Vulva, Skin grafts and flaps.
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